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陳哲鑫 副教授 兼系主任

 

 

 

陳哲鑫
副教授
電話: 02-8941-5100 轉 5301
電子郵件: jxc@cc.hwh.edu.tw
 
經    歷
 
1990        彰化師範大學學士
 
1992        清華大學碩士
 
2001        清華大學博士
 
2001~2001   中央研究院農業生物科技中心博士後研究   
 
2002~2004   美國俄亥俄州凱斯西儲大學醫學院藥理學系博士後研究
 
2004~       華夏技術學院生化工程系助理教授
 
2007       中央研究院農業生物科技中心訪問學者
 
2007~      中國生物化學暨分子生物學會會員
 
2008~2010   華夏技術學院化妝品應用系助理教授
 
2010~2011   華夏技術學院化妝品應用系助理教授兼系主任
 
2011~       華夏科技大學化妝品應用系副教授兼系主任
 
 
 
期刊論文   
 
吳紹榮、陳美均、陳哲鑫、石美芳、林宗寬 (2011) 無添加界面活性劑技術於化妝品之可行性研究,美容技術學刊 第八卷第一期,5-15
 
 
 
徐麗芬、丁貞勻、林宗寬、邱智揚、陳哲鑫 (2011)
紅花地膽草天然化合物與活性抗氧化酵素NAD(P)H:quinone oxidoreductase-1 (NQO-1)分液的分離,美容技術學刊 第八卷第一期,61-70
 
 
 
Chen, J.-H., Tsai, L.-C., Huang H.-C. and Shyur, L.-F. (2010).
Structural and catalytic roles of amino acid residues located at substrate binding pocket in Fibrobacter succinogenes 1,3-1,4-β-D-glucanase.
Proteins: structure, function, and bioinformatics. 78, 2820-2830 (SCI)
 
 
 
Shyur, L.-F., Tsung, J.-H., Chen, J.-H., Chiu, C.-Y. and Lo, C.-P. (2005). Antioxidant properties of extracts from medicinal plants popularly
used in Taiwan. Int. J. Appl. Sci. Eng. 3, 195-202
 
 
 
Lin, K.-A., Chen, J.-H., Lee, D.-F. and Lin, L.-Y. (2005).Alkaline induces metallothionein gene expression and potentiates cell proliferation in
Chinese hamster ovary cells. J. Cell. Physiol. 205, 428-436 (SCI)
 
 
 
Chen, J.-H., Huang, C.-H. and Lin, L.-Y. (2001). Rottlerin stimulates metallothionein gene expression but inhibits metal transport in Chinese
hamster ovary cells, Toxicol. Appl. Pharmacol. 177, 256-263 (SCI)
 
 
 
Chen, J.-H., Yu, C.-W. and Lin, L.-Y. (1999) in Metallothionein IV ( C. D. Klaassen Ed. ), Inactivation of metal-induced metallothionein gene
expression by protein kinase C inhibitor. p281-285, Birkhäuser Verlag, Basel, Boston, Berlin
 
 
 
Yu, C.-W., Chen, J.-H. and Lin, L.-Y. (1997) Metal-induced metallothionein gene expression can be inactivated by protein kinase C inhibitor.
FEBS Lett. 420, 69-72 (SCI)
 
 
 
Wang, S.-H., Chen, J.-H. and Lin, L.-Y. (1994) Functional integrity of metallothionein genes in testicular cell lines. J. Cell. Biochem. 55,
486-495 (SCI)
 
 
 
Chen, J.-H., Chou, Y.-T., Xu, B. and Yang, Y.-C.  CITED2 suppresses adrenomedullin gene induction by deferoxamine stimulation (under preparation)
 
 
 
Shyur, L.-F., Chen, J.-H., Hsu, Wei-Fu, and Tsai, L.-J. (2008). Directed mutagenesis of specific residues involved in substrate binding of
Fibrobacter succinogenes 1,3-1,4-b-D-glucanase. (in preparation)
 
 
 
Chen, J.-H., Hsu, Wei-Fu, Tsai, L.-J. and Shyur, L.-F. (2008). Characterization of Fibrobacter succinogenes 1,3-1,4-b-D-glucanase mutation
derived by DNA shuffling. (in preparation)
 
 
 
Chen, J.-H., Lo, C.-P., Tsung, J.-H., Chiu, C.-Y. and Shyur, L.-F. Cytotoxicity effect of tumor cell line by Sesquiterpene lactone isolated from
Elephantopus scaber. (in preparation)
 
 
 
研討會論文
 
Lie-Fen Shyur, L.-F., Hou C.-C., Huang, C.-C., Ting, C.-U., Chiu C.-Y., Lee, S.-H., Chen, J.-H. (2010) Antioxidant Response Elements (ARE) and
Xenobiotic Response Element (XRE) Are Essential for Induction of Detoxification Enzyme – NAD(P)H:quinine Oxidoredutase-1 by Fractions of
Elephentopus scaber Water Extract. The 25th Joint Ann. Conf. Biomed. Sci.
 
 
 
Chen, J.-H., Ting, C.-U., Chiu, C.-Y., Hou, C.-C. Huang, C.-C., Lee, S.-H., Shyur L.-F. (2008) Activation of Cellular NAD(P)H:quinine oxidoredutase-1
Activity by Enriched Fractions of Elephentopus scaber. The 23th Joint Ann. Conf. Biomed. Sci.
 
 
 
Chen, J.-H., Ting, C.-Y., Chiu, C.-Y.,  Hou, C.-C.,  Lee, S.-H., Shyur, L.-F. (2008) Elephentopus scaber Extracts Activate NAD(P)H:quinone
Oxidoredutase-1 Activity, A Phase II Detoxification Enzyme. ABRC 10th anniversary. International Symposium
 
 
 
Chen, J.-H., Mandrekar, S. and Yang, Y.-C. (2003) Identification of cited2 target genes by chromatin immunoprecipitation. Retreat 2002, Department of
Pharmacology, Case Western Reserve University, Cleveland, USA
 
 
 
Chen, J.-H., Hsu, W.-F. and Shyur, L.-F. (2002) Directed evolution of Fibrobacter succinogenes 1,3-1,4-D-glucanase by DNA shuffling. Abstract book for
poster session The 16th FAOBMB Symposium. P053
 
 
 
Shih, M. C., Chen, J.-H. and Lin, L.-Y. (2001) Reactive oxygen species are involved in the differential metallothionein gene expression caused by sodium
azide. The Sixteenth Joint Ann. Conf. Biomed. Sci., P116
 
 
 
Chen, J.-H., Lin, C.-H. and Lin, L.-Y. (2000) Uncoupling of metallothionein gene expression with the MRE binding activity of MTF-1. The Fifteenth Joint Ann.
Conf. Biomed. Sci., P153
 
 
 
Shih, M.-C., Chen, J.-H. and Lin, L.-Y. (2000) Differential regulation of metallothionein gene expression by sodium azide. The Fifteenth Joint Ann. Conf.
Biomed. Sci.,  P151
 
 
 
Chen, J.-H., Lin, K.-A. and Lin, L.-Y. (1999) Effect of redox potential on the metallothionein gene expression. The Fourteenth Joint Ann. Conf. Biomed. Sci.,  P235
 
 
 
Lin, K.-A., Chen, J.-H. and Lin, L.-Y. (1999) Sodium bicarbonate but not serum factors induces metallothionein gene expression during culture medium
replacement. The Fourteenth Joint Ann. Conf. Biomed. Sci., P236
 
 
 
Chen, J.-H., Yu, C.-W. and Lin, L.-Y. (1998) Involvement of protein kinase C on the metal-induced metallothionein gene expression. The Thirteenth Joint Ann.
Conf. Biomed. Sci.,  p210
 
 
產學研發
2006~2007青草茶成分地膽草中保護肝細胞的活性成分分離與其分子機制的
探討 (國科會NSC 95 - 2313 - B - 146 - 001 )- 計畫主持人
2. 2009~2010民間產學合作計畫:蟲草化妝品原料之開發-計畫主持人
 
3. 2010~2011國際合作計畫分項計畫: 「美容美體」國際證照班培訓計劃-計畫
 
共同主持人
 
4. 2011~2012民間產學合作計畫:應用於化妝品保養品之人類遺傳背景檢測平台
 
的建立-計畫主持人
 
 
 
進修研習
2010 新興醫療器材設計與開發實務
2011 醫學美容肌膚檢測基礎訓練課程
2011 醫學美容輔助人員專業課程
2011 嬰幼兒、孕婦及長者芳療理論與實務暨精油保養品調配研習
2011 經絡芳療教師技術輔導班-初階芳療研習
2011 經絡芳療教師技術輔導班-皮膚生理解剖學
2011 健康美容管理師種子教師培訓
2012 經絡芳療教師技術輔導班-芳香療法調製學
2012 經絡芳療教師技術輔導班-芳香療法核心個論
2012 美容類科健康美容本位課程整合專題研究工作坊暨課程研討會
2012 原始點推揉療法進階手法應用
            
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